NFL Week 10 ESPN New York Giants @ San Francisco 49ers Preview

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New York Giants @ San Francisco 49ers – ESPN, 8:15 PM

Manning getting the ball out quickly

Eli Manning‘s play falls off a cliff when he holds on to the ball for too long.

Beckham one of the best

Odell Beckham Jr. has continued to put up monster numbers this year, which cements his place among the league's best.

Giants run defense is missing something

Giants' former interior defensive lineman Damon Harrison was a force in the middle and will be a huge loss moving forward. In New York's one game without Harrison, they allowed 1.2 yards more per attempt and also gave up another yard after contact per attempt.

Collins racking up the stops

Safety Landon Collins has been his usual self this season and ranks in the top-10 in total stops among safeties for the fourth straight year.

Mullens was great from a clean pocket in Week 9

Nick Mullens posted the fourth-highest passer rating from a clean pocket in Week 9.

Getting the ball out quickly

Nick Mullens did his damage last week by getting rid of the ball quickly.

Buckner racking them up

DeForest Buckner has produced the fourth-most pressures among interior defenders this year.

Sherman is still the gold standard

Richard Sherman continues to be in the upper echelon of players at the position.

Key matchup

PFF Greenline has projections for the spread, moneyline and over/under of the Giants' matchup with the 49ers. Get its picks here

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