A player's injury status can have a significant effect on both real life and fantasy football. So, each week, PFF injury analyst Mario Pilato will comb through the official injury reports for each NFL game and give updates and analysis for fantasy-relevant players.
Injuries are fluid, so make sure to stay up to date by following @PFF_Mario on Twitter.
KEY
DNP: Did not participate in practice
LP: Limited participation in practice
FP: Full participation
(-): Not listed
OUT: Player will not play
D: Player is unlikely to play
Q: Player is not certain to play
NIR – Rest: Not injury-related or resting veteran
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DEN @ CLE | NYJ @ NE | KC @ TEN | CAR @ NYG | ATL @ MIA | WFT @ GB | CIN @ BAL | DET @ LAR | PHI @ LV | HOU @ ARZ | CHI @ TB |
IND @ SF | NO @ SEA
Denver Broncos @ Cleveland Browns (-1.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Mon. Status | Tues. Status | Wed. Status | Game Status |
| Teddy Bridgewater | QB | DEN | Foot | QB20 | 16.6 | LP | LP | LP | Q |
| Odell Beckham Jr. | WR | CLV | Shoulder | WR32 | 10.0 | DNP | DNP | DNP | Q |
| Noah Fant | TE | DEN | Foot | TE8 | 9.5 | LP | LP | FP | (-) |
| Melvin Gordon III | RB | DEN | Hip | RB25 | 9.0 | LP | FP | FP | (-) |
| David Njoku | TE | CLV | Knee | TE16 | 6.3 | LP | LP | FP | (-) |
| Baker Mayfield | QB | CLV | Left Shoulder | 0.4 | DNP | LP | DNP | OUT | |
| Nick Chubb | RB | CLV | Calf | 0.0 | DNP | DNP | DNP | OUT |
The Over/Under for this game is currently 40. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
New York Jets @ New England Patriots (-7)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Nick Folk | K | NE | Left Knee | K8 | 8.9 | LP | LP | LP | Q |
| Brandon Bolden | RB | NE | Thigh | RB56 | 3.5 | LP | LP | LP | Q |
| Tyler Kroft | TE | NYJ | Back | TE44 | 3.0 | DNP | DNP | DNP | OUT |
| Tevin Coleman | RB | NYJ | Hamstring | RB62 | 2.0 | (-) | (-) | LP | Q |
| Jeff Smith | WR | NYJ | Concussion | 0.0 | FP | FP | FP | (-) |
Andrew's Take: Jets tight end Ryan Griffin is an interesting punt play at tight end priced at $2,500 with Kroft ruled. He ran a route on 69% of Zach Wilson's dropbacks in Week 5.
The Over/Under for this game is currently 42.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Kansas City Chiefs @ Tennessee Titans (+4.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Tyreek Hill | WR | KC | Quad | WR3 | 22.2 | DNP | DNP | LP | Q |
| Travis Kelce | TE | KC | Neck | TE1 | 18.1 | LP | LP | FP | (-) |
| Derrick Henry | RB | TEN | NIR – Rest | RB1 | 17.6 | (-) | DNP | FP | (-) |
| A.J. Brown | WR | TEN | Illness | WR12 | 14.3 | DNP | DNP | FP | (-) |
| Julio Jones | WR | TEN | Hamstring | WR45 | 13.0 | DNP | LP | LP | Q |
| Randy Bullock | K | TEN | Shoulder | K9 | 9.2 | DNP | FP | FP | (-) |
| Jeremy McNichols | RB | TEN | Ankle | RB49 | 3.2 | DNP | LP | LP | Q |
| Michael Burton | RB | KC | Pectoral | 0.7 | DNP | DNP | DNP | OUT | |
| Khari Blasingame | RB | TEN | Shoulder | RB83 | 0.3 | LP | FP | FP | (-) |
| Blake Bell | TE | KC | Back | 0.0 | FP | FP | FP | (-) | |
| Chester Rogers | WR | TEN | Groin | WR93 | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Chiefs WR Tyreek Hill has been dealing with a quad injury for a couple of weeks. He logged two DNPs and an LP designation. I believe he will play in Week 7. Titans WR Julio Jones seemed to aggravated his hamstring in Week 6. He has logged two limited practices in row, which is encouraging. I believe he plays in Week 7 but is highly volatile.
Andrew's Take: Start Hill. He was on a snap count last week – 61% routes run per dropback – but he still saw 14 targets.
Jones should also be started in most cases because of the matchup against the Chiefs poor defense, but he is extremely risky for fear of re-injury.
Look for Nick Westbrook-Ikhine to take over slot reps with Chester Rogers ruled out.
The Over/Under for this game is currently 57.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Carolina Panthers @ New York Giants (+3)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Sterling Shepard | WR | NYG | Hamstring | WR19 | 13.8 | (-) | LP | LP | Q |
| Darius Slayton | WR | NYG | Hamstring | WR63 | 9.8 | LP | LP | LP | Q |
| Evan Engram | TE | NYG | Calf | TE14 | 8.2 | (-) | DNP | LP | Q |
| John Ross | WR | NYG | Hamstring | WR86 | 4.2 | DNP | LP | LP | Q |
| Alex Erickson | WR | CAR | Concussion | WR94 | 3.2 | LP | LP | LP | Q |
| Giovanni Ricci | RB | CAR | Concussion | 0.3 | DNP | DNP | DNP | OUT | |
| Kaden Smith | TE | NYG | Knee | 0.3 | DNP | LP | LP | (-) | |
| Saquon Barkley | RB | NYG | Ankle | 0.0 | DNP | DNP | DNP | OUT | |
| Kenny Golladay | WR | NYG | Knee | WR84 | 0.0 | DNP | DNP | DNP | OUT |
| Kadarius Toney | WR | NYG | Ankle | 0.0 | DNP | DNP | DNP | OUT | |
| Terrace Marshall Jr. | WR | CAR | Concussion | WR100 | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Giants WRs Sterling Shepard, Darius Slayton and TE Evan Engram have been questionable all week, but I believe they will play Week 7. RB Saquon Barkley and WRs Kenny Golladay and Kadarius Toney have been ruled out for Week 7. I expect them to miss next week as well.
Andrew's Take: Slayton, Ross and Engram are expected to play. Shepard is a game-time decision. Add Darius Slayton and/or Dante Pettis off the waiver wire. Slayton has seen at least six targets in both of healthy games this season. Pettis commanded 11 targets last week.
The Panthers have allowed the fifth-most receptions to opposing WRs over the last four weeks.
The Over/Under for this game is currently 42.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Atlanta Falcons @ Miami Dolphins (+2.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Tua Tagovailoa | QB | MIA | Ribs | QB14 | 19.7 | LP | LP | LP | (-) |
| DeVante Parker | WR | MIA | Shoulder / Hamstring | WR40 | 12.4 | LP | LP | LP | (-) |
| Malcolm Brown | RB | MIA | Ribs | RB58 | 4.3 | LP | LP | LP | (-) |
| Preston Williams | WR | MIA | Groin | 0.6 | LP | LP | LP | (-) | |
| Jacoby Brissett | QB | MIA | Hamstring | QB29 | 0.5 | LP | LP | LP | (-) |
| Adam Shaheen | TE | MIA | Knee | TE52 | 0.0 | FP | FP | FP | (-) |
Andrew's Take: Per Ian Rapoport, Dolphins WR DeVante Parker is listed as questionable with shoulder and hamstring ailments, and he appears to have an uphill battle to play today, source said. A chance, but not a great one. CB Xavien Howard (shoulder, groin) should be good today.
The Over/Under for this game is currently 47.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Washington Football Team @ Green Bay Packers (-7.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Terry McLaurin | WR | WAS | Hamstring | WR9 | 15.2 | FP | LP | FP | (-) |
| Antonio Gibson | RB | WAS | Shin | RB18 | 10.5 | DNP | LP | LP | Q |
| Ricky Seals-Jones | TE | WAS | Quad | TE10 | 8.0 | DNP | LP | LP | (-) |
| Dyami Brown | WR | WAS | Knee | WR52 | 7.3 | LP | LP | LP | (-) |
| Equanimeous St. Brown | WR | GB | Shoulder | WR117 | 0.3 | FP | FP | FP | (-) |
| Curtis Samuel | WR | WAS | Groin | 0.0 | DNP | DNP | DNP | OUT | |
| Cam Sims | WR | WAS | Hamstring | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Washington Football Team RB Antonio Gibson is still dealing with a shin injury. He recently received an MRI anx will continue to try to play through the injury. His injury will not get better until the team puts him on IR and lets the injury calm down. It is an extremely painful injury, so he is a risky play. WR Curtis Samuel continues to struggle with his groin injury and is missing another week. I expect Samuel to miss multiple weeks.
Andrew's Take: Antonio Gibson will be play, so use him as fantasy RB2. The Packers run defense is not great, and Gibson has only had one down week this season because he left early due to injury. Other than Week 6, he has yet to finish worse than RB28 any week this season amid his ongoing shin injury.
Dyami Brown will be the WFT's No. 2 wide receiver versus Green Bay after running the third most routes on the team last week to go along with six targets. He's a sneaky low-priced WR in DFS this week.
The Over/Under for this game is currently 47.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Cincinnati Bengals @ Baltimore Ravens (-6.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Joe Burrow | QB | CIN | Throat | QB10 | 21.1 | FP | FP | FP | (-) |
| Chris Evans | RB | CIN | Hamstring | RB52 | 3.2 | FP | LP | FP | (-) |
| Mike Thomas | WR | CIN | Ankle | 0.6 | FP | FP | FP | (-) | |
| Latavius Murray | RB | BLT | Ankle | RB64 | 0.0 | DNP | DNP | DNP | OUT |
| Sammy Watkins | WR | BLT | Thigh | WR95 | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Ravens RB Latavius Murray and WR Sammy Watkins have both been ruled out for Week 7 for an ankle and thigh, respectively.
Andrew's Take: Rookie Rashod Bateman will start for Watkins as the Ravens No. 2 wide receiver. A solid No. 3 WR fantasy option for Week 7. Great play in cash formats on DraftKings at $3,400 after he saw six targets a week ago. He is extremely popular at `10.5% projected rostership.
Take a flier on Devonta Freeman among the RBs in the Baltimore backfield. Freeman has passed the eye test in limited action the past few weeks.
Also, Ty’Son Williams will likely be active with Murray out.
Williams easily offers the most explosiveness — he has the No. 1 breakaway run rate at the position this season. He’d be the dart-throw to add for free off waivers, followed by Freeman who has averaged 5.9 yards per carry and 11.3 yards per reception this season.
In all likelihood, this backfield will be a three-headed monster that should be avoided. But with six teams on bye, he's not the worst desperation play.
The Over/Under for this game is currently 46. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Detroit Lions @ Los Angeles Rams (-16.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| D'Andre Swift | RB | DET | Groin | RB7 | 14.1 | LP | LP | LP | Q |
| T.J. Hockenson | TE | DET | Knee | TE5 | 10.1 | DNP | LP | LP | Q |
| Sony Michel | RB | LA | Shoulder | RB39 | 6.0 | DNP | LP | LP | Q |
| DeSean Jackson | WR | LA | NIR – Rest | WR60 | 5.5 | (-) | (-) | DNP | (-) |
| Jason Cabinda | RB | DET | Hip | 0.5 | DNP | LP | LP | Q |
Mario's Take: Lions RB D'Andre Swift and TE T.J. Hockenson have been dealing with their season long injury designations, but they will play in Week 7. Rams RB Sony Michael is dealing with a shoulder injury, but I expect him to be ready for Week 7.
The Over/Under for this game is currently 50.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Philadelphia Eagles @ Las Vegas Raiders (-3)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Dallas Goedert | TE | PHI | Illness | TE6 | 8.8 | (-) | DNP | LP | (-) |
| Sony Michel | RB | LA | Shoulder | RB39 | 6.0 | DNP | LP | LP | Q |
| DeSean Jackson | WR | LA | NIR – Rest | WR60 | 5.5 | (-) | (-) | DNP | (-) |
Andrew's Take: Darren Waller appears to be extremely questionable with an ankle injury. If he's active you play him. His upside is too great to bench. However, smart managers would be wise to add Cole Kmet as a backup plan in case Waller cannot go. He plays in the late afternoon like the Raiders, so it provides you more time to wait on Waller.
Waller's absence also gives guys like Ruggs and Renfrow a opportunity to see a larger portion of team targets. Renfrow has a super safe floor, with Ruggs providing more of the boom potential.
if you are waiting on Darren Waller news just add Cole Kmet as a backup because he also plays in the late window of game.
Like his matchup versus Tampa
— Andrew Erickson™ (@AndrewErickson_) October 24, 2021
The Over/Under for this game is currently 48.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Houston Texans @ Arizona Cardinals (-17.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Brandin Cooks | WR | HST | NIR – Rest | WR14 | 16.9 | DNP | (-) | (-) | (-) |
| DeAndre Hopkins | WR | ARZ | NIR – Rest | WR6 | 16.7 | DNP | (-) | (-) | (-) |
| Chase Edmonds | RB | ARZ | Shoulder | RB16 | 13.1 | LP | LP | FP | (-) |
| Nico Collins | WR | HST | Foot | WR59 | 7.1 | (-) | LP | LP | Q |
| Chris Conley | WR | HST | Neck | WR72 | 4.1 | LP | LP | LP | Q |
| Danny Amendola | WR | HST | Thigh | WR116 | 3.0 | FP | FP | FP | (-) |
| Darrell Daniels | TE | ARZ | Hamstring | 0.3 | DNP | DNP | DNP | OUT | |
| Deshaun Watson | QB | HST | NIR | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Texans WR Nico Collins has been dealing with a foot issue, but I expect him to play in Week 7.
Andrew's Take: The quintessential pivot to Bateman in GPPs is another rookie wide receiver, Nico Collins at $3,200. Shoutout to PFF fantasy analyst Jarad Evans for the idea.
Collins and Bateman saw nearly identical usage in their first games back from injury, as both ran a route on 67% of dropbacks while commanding six targets. The only difference is Collins scored more real fantasy and expected fantasy points.
With a better matchup on paper and a 12% rostership projection difference, Collins is the leverage play in GPPs.
The Over/Under for this game is currently 47.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Chicago Bears @ Tampa Bay Buccaneers (-12.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Tom Brady | QB | TB | Right Thumb | QB4 | 28.7 | FP | FP | FP | (-) |
| Darnell Mooney | WR | CHI | Groin | WR28 | 12.5 | LP | LP | FP | (-) |
| Allen Robinson II | WR | CHI | Ankle | WR25 | 12.3 | DNP | LP | LP | Q |
| Ryan Succop | K | TB | Back | K4 | 8.3 | FP | FP | FP | (-) |
| O.J. Howard | TE | TB | Ankle | TE22 | 7.2 | DNP | LP | FP | Q |
| Khalil Herbert | RB | CHI | Shoulder | RB29 | 6.3 | FP | FP | FP | (-) |
| Giovani Bernard | RB | TB | Knee/Chest | RB41 | 5.5 | FP | FP | FP | (-) |
| Rob Gronkowski | TE | TB | Ribs | TE37 | 0.0 | DNP | DNP | DNP | OUT |
| Jimmy Graham | TE | CHI | NIR – Rest | TE45 | 0.0 | DNP | FP | DNP | (-) |
| J.P. Holtz | TE | CHI | Quad | 0.0 | LP | LP | FP | Q | |
| Antonio Brown | WR | TB | Ankle | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Bears WR Allen Robinson has been dealing with an ankle injury, but I expect him to play in Week 7. Bucs TE Rob Gronkowski and WR Antonio Brown have been ruled out for Week 7.
Andrew's Take: With Antonio Brown ruled out, Chris Godwin and Mike Evans both become top-10 wide receivers options. And fantasy managers who are in a pinch looking for a Brown replacement can turn to Johnson.
The former Golden Gopher has the No. 3 wide receiver job all to himself with Scotty Miller still on injured reserve. In Week 3 without Brown in the lineup, Johnson caught three passes for 63 yards on six targets (21% target rate per route run).
He's a fantasy WR3 with some upside for fantasy managers who are desperate due to players on bye weeks and injuries.
If you need a replacement for Antonio Brown add Tyler Johnson.
3 catches for 63 yards on six targets replacing A.B. in Week 3.
Went 4 for 61 on six targets vs the Bears last season filling in for Chris Godwin pic.twitter.com/d5McsLARI0
— Andrew Erickson™ (@AndrewErickson_) October 22, 2021
The Over/Under for this game is currently 47. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Indianapolis Colts @ San Francisco 49ers (-4)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| Jimmy Garoppolo | QB | SF | Calf | QB22 | 18.0 | LP | LP | FP | (-) |
| T.Y. Hilton | WR | IND | Quad | WR64 | 9.5 | DNP | DNP | DNP | Q |
| Jack Doyle | TE | IND | NIR – Rest | TE30 | 3.6 | (-) | DNP | FP | (-) |
| Jordan Wilkins | RB | IND | NIR – Rest | 0.0 | DNP | DNP | DNP | OUT | |
| Nick Williams | WR | SF | Knee | 0.0 | DNP | LP | FP | (-) | |
| Trey Lance | QB | SF | Knee | QB28 | 0.0 | DNP | DNP | DNP | OUT |
Mario's Take: Colts WR T.Y. Hilton has been dealing with a quad soft tissue injury. He has been an DNP all week, and has been ruled out.
49ers QB Trey Lance has been ruled out with a knee injury suffered in Week 5. I do not expect him to miss a significant amount of time.
Andrew's Take: Nothing to do with injuries, but the weather in this game looks #bad. 17 mph-plus winds with rain. Look to pivot off receivers and quarterbacks in this matchup.
The Over/Under for this game is currently 43. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
New Orleans Saints @ Seattle Seahawks (+4.5)
| Name | Position | Team | Injury | Fantasy Rank | Proj. points | Thurs. Status | Fri. Status | Game Status |
| Alex Collins | RB | SEA | Groin | RB24 | 9.7 | DNP | DNP | (-) |
| Taysom Hill | QB | NO | Concussion | QB27 | 7.9 | DNP | DNP | (-) |
| Freddie Swain | WR | SEA | Ribs | WR67 | 6.0 | FP | (-) | (-) |
| Deonte Harris | WR | NO | Hamstring | WR70 | 3.1 | DNP | DNP | (-) |
| Chris Hogan | WR | NO | NIR – Rest | WR114 | 1.7 | DNP | DNP | (-) |
| Dwayne Washington | RB | NO | Neck | RB72 | 1.5 | DNP | DNP | (-) |
Andrew's Take: Per Adam Schefter, Seahawks’ RB Alex Collins, listed as questionable for Monday Night Football vs. Saints, is expected to play, per HC Pete Carroll.
Meanwhile, Saints ruled out QB Taysom Hill (concussion) and WR Deonte Harris (hamstring) for Monday night vs. the Seahawks.
Collins is the one startable asset, but with Rashaad Penny returning from IR he's a RB3 in a bad matchup versus the New Orleans Saints stout run defense.
With no Deonte Harris or Taysom Hill, expect Marquez Callaway to be the leading WR for the Saints even with Tre'Quan Smith making his return.
The Over/Under for this game is currently 42.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
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