In a Week 4 divisional battle between AFC South foes, the Tennessee Titans re-established their prowess with a wire-to-wire 24-17 victory over the Indianapolis Colts. The victory brings the Titans to .500 through four weeks.
Offensive spotlight: Derrick Henry crossed the century mark for the first time in 2022 on just 20 carries. Seventy-nine of his 112 rush yards were after contact, and he finished with four explosive run plays, five rushing first downs and his third rushing score of the year.
Defensive spotlight: Two total pressures, a hurry and a sack, completed a solid edge-rushing day from veteran Denico Autry on only 10 pass-rushing snaps. He is on pace to finish with a 90.0-plus pass-rushing grade.
Rookie spotlight: For a second consecutive week, Treylon Burks didn’t garner at least five targets within the Titans’ passing game. The first-rounder caught two of his three targets for just 16 yards before he left the game in the fourth with a leg injury. He finished the afternoon with his second-lowest receiving grade of the year (53.7), pending review.
Offensive line spotlight: Aaron Brewer was one of the solid bright spots along the Titans’ offensive line that paved the way for a ground-first offensive attack. Brewer registered 70.0-plus grades as a run-blocker and pass-blocker on a combined 56 snaps, pending review.
Box Score
Passing
| Tennessee Titans | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Ryan Tannehill | 14.38 | 17 / 21 | 137 | 6.5 | 2 | 0 |
| Indianapolis Colts | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Matt Ryan | 22.84 | 27 / 37 | 356 | 9.6 | 2 | 1 |
Rushing
| Tennessee Titans | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Derrick Henry | 26.7 | 22 | 114 | 5.2 | 1 | 19 |
| Ryan Tannehill | 14.38 | 5 | 9 | 1.8 | 0 | 9 |
| Treylon Burks | 3.8 | 1 | 4 | 4 | 0 | 4 |
| Indianapolis Colts | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Matt Ryan | 22.84 | 2 | -4 | -2 | 0 | 2 |
| Jonathan Taylor | 4.3 | 20 | 42 | 2.1 | 0 | 11 |
| Nyheim Hines | 2.3 | 1 | 0 | 0 | 0 | 0 |
Receiving
| Tennessee Titans | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Derrick Henry | 26.7 | 5 | 3 | 33 | 6.6 | 0 |
| Robert Woods | 13 | 4 | 4 | 30 | 7.5 | 1 |
| Chigoziem Okonkwo | 12.8 | 3 | 3 | 38 | 12.7 | 1 |
| Dontrell Hilliard | 5.8 | 4 | 4 | 18 | 4.5 | 0 |
| Treylon Burks | 3.8 | 3 | 2 | 14 | 4.7 | 0 |
| Austin Hooper | 1.4 | 1 | 1 | 4 | 4 | 0 |
| Kyle Philips P | 0 | 1 | 0 | 0 | 0 | 0 |
| Indianapolis Colts | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Mo Alie-Cox | 26.5 | 6 | 6 | 85 | 14.2 | 2 |
| Alec Pierce | 12 | 6 | 4 | 80 | 13.3 | 0 |
| Kylen Granson | 10.2 | 4 | 4 | 62 | 15.5 | 0 |
| Parris Campbell | 8.3 | 4 | 4 | 43 | 10.8 | 0 |
| Michael Pittman Jr. | 6.1 | 6 | 3 | 31 | 5.2 | 0 |
| Jelani Woods | 4.3 | 1 | 1 | 33 | 33 | 0 |
| Jonathan Taylor | 4.3 | 3 | 1 | 1 | 0.3 | 0 |
| Ashton Dulin | 3.8 | 3 | 2 | 18 | 6 | 0 |
| Nyheim Hines | 2.3 | 2 | 2 | 3 | 1.5 | 0 |
| Mike Strachan | 0 | 1 | 0 | 0 | 0 | 0 |
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