A player's injury status can have a significant effect on both real-life and fantasy football. So, each week, PFF injury analyst Mario Pilato will comb through the official injury reports for each NFL game and give updates and analysis for fantasy-relevant players.
Injuries are fluid, so make sure to stay up to date by following @PFF_Mario on Twitter.
| LV @ PIT | BUF @ MIA | NO @ CAR | HST @ CLV |
LAR @ IND | CIN @ CHI | SF @ PHI | DEN @ JAX | NE @ NYJ |
ATL @ TB | MIN @ ARZ | TEN @ SEA | DAL @ LAC |
KC @ BLT | DET @ GB
Las Vegas Raiders @ Pittsburgh Steelers (-6.5)
Mario's Take: Mariota reaggravated a quad strain during his 31-yard run on Monday Night Football. He is out, and I believe he is suffering from a Grade 1 strain, RTP 2-3 weeks.
Jacobs has been ruled out with a toe and ankle issue. He had been playing through a turf toe injury but then suffered an ankle sprain during the Monday Night Football game. Jacobs initially came out of the game to get taped and ended up coming out of the game hobbling multiple times. I think the former Alabama running back may miss more than just this week, but I expect him to be back for the matchup with the Chargers in Week 4 at the latest.
Fantasy Football Impact: Jacobs is officially out for the Raiders, which means the backfield will be headed by Kenyan Drake and Peyton Barber. Don't expect either to produce much on the ground against the league's best run defense. Drake can slide in as backend RB3 due to his work in the passing game. He is not worth targeting in DFS, even at a suppressed cost due to his capped ceiling.
The current over/under for this game is 47. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Buffalo Bills @ Miami Dolphins (+3.5)
Mario's Take: Diggs recorded a DNP Friday for what was most likely a vet day. No need to fret: He will play in Week 2.
The current over/under for this game is 47.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
New Orleans Saints @ Carolina Panthers (+3.5)
| Team | Name | Position | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| CAR | Shi Smith | WR | Shoulder | 0.3 | FP | FP | FP | (-) |
Mario's Take: I expect Smith to make his season debut in Week 2.
The current over/under for this game is 44.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Houston Texans @ Cleveland Browns (-13)
Mario's Take: Brown is suffering from an ankle and shoulder injury. He didn't practice early in the week but got a limited practice in Friday. I expect Brown to play against his former team in Week 2.
Fantasy Football Impact: Rookie Anthony Schwartz is questionable. If he can't go, look for Donovan Peoples-Jones to take over WR2 duties — he is a solid DFS dart throw at an extremely cheap cost.
The current over/under for this game is 48. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Los Angeles Rams @ Indianapolis Colts (+3.5)
Mario's Take: Jackson recorded a DNP Friday, but it was due to a vet day.
Campbell and Pittman Jr. were both added to the injury report Friday. They need to be monitored closely as kickoff approaches.
The current over/under for this game is 48. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Cincinnati Bengals @ Chicago Bears (-2.5)
Mario's Take: N/A
The current over/under for this game is 45. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
San Francisco 49ers @ Philadelphia Eagles (+3)
Mario's Take: Sanders is dealing an ankle injury, but his practice activity has increased throughout the week. I do not believe the injury is serious: He will play in Week 2.
Ertz has been dealing with a minor hamstring strain, but he increased his practice activity throughout the week. I expect Ertz to play in Week 2.
The current over/under for this game is 49.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Denver Broncos @ Jacksonville Jaguars (+6)
| Team | Name | Position | Injury | Fantasy Rank | Proj. points | Wed. Status | Thurs. Status | Fri. Status | Game Status |
| DEN | Noah Fant | TE | Knee | TE7 | 11.7 | FP | FP | FP | (-) |
Mario's Take: N/A
The current over/under for this game is 45. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
New England Patriots @ New York Jets (+6)
Mario's Take: Smith has been dealing with a hip injury and has been a limited participant for the majority of the week. I believe Smith will be ready to go for Week 2.
Crowder has been dealing with a groin issue and COVID protocol. He practiced in a limited fashion all week but will be unable to go in Week 2.
Cole missed Week 1 due to a knee sprain and has practiced in a limited fashion this whole week. I am optimistic he plays in Week 2 even though he is considered a game-time decision.
The current over/under for this game is 43. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Atlanta Falcons @ Tampa Bay Buccaneers (-12.5)
Mario's Take: I believe Brown and Gronkowski received vet days on Friday and will play in Week 2.
The current over/under for this game is 52. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Minnesota Vikings @ Arizona Cardinals (-3.5)
Mario's Take: N/A
The current over/under for this game is 50.5 PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Tennessee Titans @ Seattle Seahawks (-6.5)
Mario's Take: Firkser recorded a DNP Friday after being limited earlier in the week. I believe Firkser is truly a game-time decision, and he needs to be monitored closely.
Penny left the Week 1 game early with a calf injury. He is listed as doubtful, and I expect him to miss a week or two.
The current over/under for this game is 54. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Dallas Cowboys @ Los Angeles Chargers (-3.5)
N/A
The current over/under for this game is 55. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Kansas City Chiefs @ Baltimore Ravens (+3.5)
Mario's Take: Brown logged two DNPs early in the week with an ankle injury but was taken off of the report Friday. He will play in SNF.
Duvernay has been dealing with a groin issue, but I believe he will play in SNF, given his limited participation tag.
The current over/under for this game is 54.5 PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
Detroit Lions @ Green Bay Packers (-11.5)
Mario's Take: Williams and Deguara are in the five-step concussion protocol. They both are not even to the sport specific activities, so I do not believe they will be ready for MNF.
The current over/under for this game is 48. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.
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