• Best Bet: New York Giants +3.5
• All odds and game spreads courtesy of BetMGM
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New York Giants at New York Jets
| Spread | Total | Moneyline | |
| New York Giants | +3.5 (-110) | O 38 (-110) | +185 |
| New York Jets | -3.5 (-110) | U 38 (-110) | -225 |
Bet New York Giants +4.5
The two New York teams appear to be setting up opposite plans for their quarterback room this Sunday. The Jets need to leave Week 3 with a healthy Joe Flacco to provide some semblance of play for their upcoming Week 1 game. The Giants should still see some run for both Daniel Jones and Tyrod Taylor, if there is any sort of quarterback controversy. The Giants should be ahead early and able to coast to an easy covered victory, especially if we see both teams not play or play starters sparingly on Sunday.
Detroit Lions at Pittsburgh Steelers
| Spread | Total | Moneyline | |
| Detroit Lions | +6 (-110) | O 39.5 (-110) | +180 |
| Pittsburgh Steelers | -6 (-110) | U 39.5 (-110) | -225 |
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