Fantasy Football: 5 WR/CB matchups to target and 5 to avoid in Week 6

Week 6 of the fantasy football wide receiver-cornerback matchups to target and avoid features a veteran player with WR1 upside, as well as two rookies who land on either end of the start-sit spectrum.

Utilize PFF’s WR/CB matchup chart and in-depth coverage data to help you set the best lineups for Week 6 and the rest of the season.

Click here for more PFF tools:

Rankings & Projections | WR/CB Matchup Chart | NFL & NCAA Betting Dashboards | NFL Player Props tool | NFL & NCAA Power Rankings

5 WR/CB Matchups to Target

Buffalo Bills WR Stefon Diggs vs. Tennessee Titans CB Jackrabbit Jenkins

Diggs has thoroughly disappointed so far, ranking as the WR25 through five weeks. However, this should be the week he turns it around. He harbors WR1 upside in this contest because his target share has remained at an elite 26.8% clip, and he now has a relatively easy matchup with the Titans.

No single defense has allowed more receiving yardage to opposing wide receivers than Tennessee's at 1,122. It's also only a league-average defense in limiting explosive pass plays at 21.8%.

Both marks bode well for a Bills offense that has the 11th-most passing yards and 20th-highest 14.2% explosive pass percentage this season. The opportunities are there, and now Diggs finally has the matchup in a smash spot this weekend.

Cincinnati Bengals WR Ja’Marr Chase vs. Detroit Lions CB Jerry Jacobs

It took all of zero weeks for Chase to translate to the NFL, as he holds the WR8 position so far with an absurd 98.4 fantasy points. Even with all of the Bengals’ receivers returning to the field in Week 5, it was Chase who led the team with nine targets and a 25.7% target share.

Every Ja’Marr Chase preseason tweet should be deleted if not done so already. He’s going OFF.

pic.twitter.com/ffqSU13qGQ

— Ari Meirov (@MySportsUpdate) October 10, 2021

He’s been big-play reliant this season, but that shouldn’t be an issue in a battle against the Lions. Through five weeks, only one defense has conceded more deep receiving yards than the Lions’ 459.

PFF’s strength of schedule (SoS) metric also grades the Bengals’ receiver matchup as the easiest this week.