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Fantasy Football: Week 5 OL/DL matchups to target and avoid

2WF6AAT San Francisco 49ers quarterback Brock Purdy (13) and offensive tackle Trent Williams (71) celebrate after a touchdown run by Elijah Mitchell during the second half of the NFC Championship NFL football game against the Detroit Lions in Santa Clara, Calif., Sunday, Jan. 28, 2024. (AP Photo/Mark J. Terrill)

Xavier Worthy is set for lift-off: While absorbing a larger role due to injuries in the Kansas City Chiefs wide receiver corps, Worthy has a chance to come through on his massive ceiling this week as well.

A quieter start to the season should come to an end this week for Josh Jacobs: His underlying metrics and positive matchup this week point to his first potential top-12 finish on the year.

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Estimated reading time: 6 minutes


Whether you’re looking for some important tie-breakers in fantasy start/sit decisions or an advantage in DFS, knowing which players have the most and least beneficial matchups each week can help.

Understanding which teams have the advantage in the trenches can be a key to weekly fantasy football results. These are some of the more crucial matchups to be aware of as fantasy managers head into Week 5.

Click here to see this week’s entire offensive line/defensive line matchup tool on PFF.com.


Offensive line matchups to target

Kansas City Chiefs versus New Orleans Saints

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