NFL Betting 2022: Six futures bets to consider ahead of the season

• With the Titans having lost plenty of talent this offseason, consider a bet on the Indianapolis Colts to win the AFC South (-140) in 2022.

• New Vikings head coach Kevin O'Connell could push quarterback Kirk Cousins to greater passing heights, making the over on his touchdown prop (31.5, -115) a worthwhile bet.

• James Conner found the end zone 15 times on the ground in 2021, and he's poised to replicate that success in 2022. Bet him as a long shot to lead the NFL in rushing touchdowns (+2800) this season.

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We are just a few days away from the start of the 2022 NFL season. So here are the six futures bets you need to place before the first game of the year kicks off on Thursday night.

Note: All odds sourced from BetMGM Sportsbook as of Sept. 5.

Indianapolis Colts To Win AFC South: (-140)

It's hard to believe, but the Colts have not won the AFC South since the 2014 season. They've finished second in three of the past four years yet have averaged over 9.25 wins during that same time. 

But the 2022 season appears to be their year, as the Tennessee Titans have lost a ton of talent his offseason. They traded A.J. Brown to the Philadelphia Eagles, and their top pass-rusher in Harold Landry III tore his ACL last week. The Jacksonville Jaguars and Houston Texans are still a few years away from contending, as their rosters don't stack up against the Colts' group.

Indianapolis is the current favorite in the division, and it’s not hard to see why. They have the best roster in the division, and the upgrade from Carson Wentz to Matt Ryan should be worth at least two or three wins. Plus, the defense should be even better this season with the addition of Stephon Gilmore, who earned a 79.4 coverage grade last season with the Panthers. 

Look for the Colts to win at least double-digit games this season and take home the division.