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NFL Week 16 same-game parlays

2YPYY0T San Francisco 49ers quarterback Brock Purdy scrambles against the Buffalo Bills during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 1, 2024. (AP Photo/Gene J. Puskar)

Same-game parlays (SGPs) allow you to combine multiple bets from a single game into one wager, increasing the potential payout.

Our SGP picks are built around specific game narratives that the data suggests could unfold, with insight into how key players and matchups may impact the outcome.

Here are our top SGP picks for this week based on these data-driven narratives.

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